- any game played with a ball, especially baseball or softball.
- a situation and all its attendant circumstances: Having a new administration in power changes the entire ball game at city hall.
- a ceremonial game of both ritual and sporting significance, played by teams on a ball court in Mesoamerican cultures from the Preclassic period to the Spanish conquest.
- any game played with a ball
- a game of baseball
- a situation; state of affairs (esp in the phrase a whole new ball game)
