- a creature, variously described as a serpent, lizard, or dragon, said to kill by its breath or look.
- any of several tropical American iguanid lizards of the genus Basiliscus, noted for their ability to run across the surface of water on their hind legs.
- (in classical legend) a serpent that could kill by its breath or glance
- any small arboreal semiaquatic lizard of the genus Basiliscus of tropical America: family Iguanidae (iguanas). The males have an inflatable head crest, used in display
- a 16th-century medium cannon, usually made of brass
