- a member of a tribe of North American Indians, the smallest tribe of the Iroquois Confederacy.
- the dialect of the Seneca language spoken by the Cayuga.
- one of an American breed of domestic ducks having black plumage.
- a member of a Native American people (one of the Iroquois peoples) formerly living around Cayuga Lake
- the language of this people, belonging to the Iroquoian family