- any of several volatile, inert, saturated compounds of carbon, fluorine, chlorine, and hydrogen: used as refrigerants, foam-blowing agents, solvents, and, formerly, as aerosol propellants until scientists became concerned about depletion of the atmospheric ozone layer.
- any of various gaseous compounds of carbon, hydrogen, chlorine, and fluorine, used as refrigerants, aerosol propellants, solvents, and in foam: some cause a breakdown of ozone in the earth's atmosphere