- (no longer in technical use) a congenital disease due to absence or deficiency of normal thyroid secretion, characterized by physical deformity, dwarfism, and intellectual disability, and often by goiter: This condition is now diagnosed as congenital hypothyroidism or congenital iodine deficiency.
- a condition arising from a deficiency of thyroid hormone, present from birth, characterized by dwarfism and mental retardation
