- the act or process of rendering an alcohol unfit for drinking by adding an unwholesome substance that does not alter its usefulness for other purposes: New legislation made the denaturation of industrial alcohol compulsory.
- the act or process of altering the original state of a protein or the like through chemical or physical means: Acid and heat both cause a denaturation of protein, breaking bonds in the protein’s secondary and tertiary structure.
- the act or process of depriving something of its natural character or properties: Totalitarianism emerges from the denaturation of religion and politics.