- to render (any of various alcohols) unfit for drinking by adding an unwholesome substance that does not alter usefulness for other purposes.
- to treat (a protein or the like) by chemical or physical means so as to alter its original state.
- to make (fissionable material) unsuitable for use in an atomic weapon by mixing it with unfissionable material.
- to deprive (something) of its natural character, properties, etc.
- to change the nature of
- to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc
- to render (something, such as ethanol) unfit for consumption by adding nauseous substances
- to render (fissile material) unfit for use in nuclear weapons by addition of an isotope
