- an amendment to the U.S. Constitution, ratified in 1791 as part of the Bill of Rights, providing chiefly that people cannot be required to testify against themselves in a criminal case and that no person be subjected to a second trial for an offense for which they have been duly tried previously.
- an amendment to the US Constitution stating that no person may be compelled to testify against himself and that no person may be tried for a second time on a charge for which he has already been acquitted
- to refuse to answer a question on the grounds that it might incriminate oneself