- a confederacy of Iroquoian Indians: the Mohawk, Oneida, Onondaga, Cayuga, and Seneca, and, after the 18th century, the Tuscarora.
- (formerly) a confederacy of North American Indian peoples living mainly in and around present-day New York state, consisting of the Cayugas, Mohawks, Oneidas, Onondagas, and Senecas
