- hopelessly bad; terrible: What kind of twisted, fucked-up, disturbed logic is that?
- seriously hurt or damaged:I was just in a bike accident and my hand's still fucked up.The song lyrics paint a twisted portrait of a severely fucked-up young man.
- unfair or biased: This is one fucked-up game—you can’t ever win without buying a ton of new lives.
- intoxicated or high on drugs:Next thing we knew, the fucked-up dude was trying to climb the Hollywood sign.