- overrun to an unwanted degree or in a troublesome manner by predatory animals or vermin (often used in combination): It is so difficult to eradicate cockroaches from an infested area.The only unguarded way of escape was through an alligator-infested swamp.
- filled or riddled with anything undesirable or troublesome (usually used in combination): The restaurant sat in an increasingly tourist-infested part of town.
- the simple past tense and past participle of infest.