- a goddess of fertility, the sister and wife of Osiris and mother of Horus, and usually represented as a woman with a cow's horns with the solar disk between them: later worshiped in the Greek and Roman empires.
- Islamic State in Iraq and al-Sham (or Islamic State in Iraq and Syria): a radical Sunni Muslim organization whose aim is to restore an Islamic state, or caliphate, in the region encompassing Syria, Lebanon, Israel, Jordan, the Palestinian territories, and southeastern Turkey.
- the local name for the River Thames at Oxford
- an ancient Egyptian fertility goddess, depicted as a woman with a cow's horns, between which was the disc of the sun; wife and sister of Osiris