- a village in E Virginia: first permanent English settlement in North America 1607; restored 1957.
- a city in SW New York.
- a city in central North Dakota.
- a seaport in and the capital of St. Helena, in the S Atlantic Ocean.
- a ruined village in E Virginia, on Jamestown Island (a peninsula in the James River): the first permanent settlement by the English in America (1607); capital of Virginia (1607–98); abandoned in 1699
