- to manage or influence skillfully, especially in an unfair manner: to manipulate people's feelings.
- to handle, manage, or use, especially with skill, in some process of treatment or performance: to manipulate a large tractor.
- to adapt or change (accounts, figures, etc.) to suit one's purpose or advantage.
- to examine or treat by skillful use of the hands, as in palpation, reduction of dislocations, or changing the position of a fetus.
- to handle or use, esp with some skill, in a process or action
- to negotiate, control, or influence (something or someone) cleverly, skilfully, or deviously
- to falsify (a bill, accounts, etc) for one's own advantage
- (in physiotherapy) to examine or treat manually, as in loosening a joint
