- a region in central Italy, bordering the Adriatic. 3,743 sq. mi. (9,695 sq. km).
- the border area between England and Wales or Scotland, both characterized by continual feuding (13th–16th centuries)
- a region of central Italy. Capital: Ancona. Pop: 1 484 601 (2003 est). Area: 9692 sq km (3780 sq miles)
- any of various other border regions
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