- any of several Old World boa constrictors of the subfamily Pythoninae, often growing to a length of more than 20 feet (6 meters): the Indian python, Python molurus, is endangered.
- a spirit or demon.
- a person who is possessed by a spirit and prophesies by its aid.
- a large dragon who guarded the chasm at Delphi from which prophetic vapors emerged. He was finally killed by Apollo, who established his oracle on the site.
- an open-source, high-level programming language known for its readability and support for multiple programming styles, and, due to its many libraries, a large range of applications.
- any large nonvenomous snake of the family Pythonidae of Africa, S Asia, and Australia, such as Python reticulatus (reticulated python). They can reach a length of more than 20 feet and kill their prey by constriction
- a dragon, killed by Apollo at Delphi
