- a seaport in northwestern Colombia.
- a cactus, Heliocereus speciosus, of Mexico and Central America, having scarlet flowers 6–7 inches (15–17 centimeters) long.
- a port in NW Colombia, on the Caribbean: the oldest city in Colombia, founded in 1525; terminus of the Atlantic railway from Bogotá (opened 1961). Pop: 454 000 (2005 est)