- by an ample or considerable amount; quite a lot: As a professor, my workload is substantially reduced or eliminated during the summer months.
- in a basic or essential way; fundamentally: The new law mandates equal pay for substantially similar work, whether at the same establishment or not.
- in a solid or firm way; stoutly or sturdily: In the far north, homes take more fuel to heat and also have to be built more substantially.
- in a corporeal or material way; physically: The Eucharist makes the very Person of Christ truly, really, and substantially present in the consecrated bread and wine.