- a state in SE central Mexico. 1,554 sq. mi. (4,025 sq. km). Capital: Tlaxcala.
- a state of S central Mexico: the smallest Mexican state; formerly an Indian principality, the chief Indian ally of Cortés in the conquest of Mexico. Capital: Tlaxcala. Pop: 961 912 (2000 est). Area: 3914 sq km (1511 sq miles)
- a city in E central Mexico, on the central plateau, capital of Tlaxcala state: the church of San Francisco (founded 1521 by Cortés) is the oldest in the Americas. Pop: 15 777 (2005)
