- a wild South American ruminant, Vicugna vicugna, of the Andes, related to the guanaco but smaller, and yielding a soft, delicate wool: an endangered species, now increasing in numbers.
- a fabric of this wool or of some substitute, usually twilled and finished with a soft nap.
- a garment, especially an overcoat, of vicuna.
- a tawny-coloured cud-chewing Andean artiodactyl mammal, Vicugna vicugna, similar to the llama: family Camelidae
- the fine light cloth made from the wool obtained from this animal
