- a benign encysted tumor of the skin, especially on the scalp, containing sebaceous matter; a sebaceous cyst.
- a large, crowded city or a crowded urban district: London is the great wen of England.
- wynn.
- a sebaceous cyst, esp one occurring on the scalp
- a large overcrowded city (esp London in the phrase the great wen)
- a rune having the sound of Modern English w