- any of various uncultivated species of lettuce, growing as weeds in fields and waste places, especially a North American species, Lactuca canadensis.
- any of several uncultivated lettuce plants, such as Lactuca serriola (or L. scariola) of Eurasia and L. canadensis (horseweed) of North America, which grow as weeds and have yellow or blue flowers, milky juice in the stem, and prickly leaves: family Asteraceae (composites)
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