- a major league, as in baseball: His debut in the big leagues was as a relief pitcher for the Dodgers in the final game of the regular season.
- the area of greatest competition, highest achievement or rewards, etc.: He's a local politician who isn't ready for the big league.
- of or belonging to a major league: a big-league pitcher.
- among the largest, foremost, etc., of its kind: the big-league steel companies.